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Coexistence of relapsing polychondritis and remitting seronegative symmetrical synovitis with pitting odema (RS3PE) syndrome

Dilek Tezcan, Semral Gulcemal, Muhammet Limon & Sema Yilmaz

Relapsing Polychondritis (RP) is an autoimmune disease characterized by recurrent and progressive inflammation and destruction of cartilaginous and other proteoglycan-rich tissue with multisystematic manifestations. Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE), is a rare disorder characterized by pitting edema, onset of acute polyarthritis and negative rheumatoid factor. A 46-year-old female patient who developed RS3PE after RP symptoms developed. This case, being an RS3PE syndrome accompanying RP and being a rare association, is presented to contribute to the literature.