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Highly effective of stabilized silver nanocatalyst of ibuprofen and paracetamol drugs for the degradation of heterogeneous doxycycline activity

Ajit Kumar Varma, Rakesh Patel

The formation of the Dox-Ag (0) NPs was monitored by using UV–Vis absorption spectroscopy which are confirmed the formation of Dox-Ag (0) NPs to exciting the typical surface plasma on absorption maxima at 404 nm. Transmission electron microscopy (TEM) confirmed the spherical morphology and monodispersed Dox-Ag (0) NPs with particle size 6.84 ± 2.2 nm.Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline The drug is a secondgeneration tetracycline, exhibiting lesser toxicity than first-generation tetracyclines which are used to treat a wide range of bacterial infections, depending on the results of antibiotic susceptibility testing.Mycoplasmahominis, Escherichia coli, Pseudomonas aeruginosa and Gram-positive bacteria Staphylococcus aureus, Micrococcus flavus and Micrococcus luteus by the disk diffusion method. The antimicrobial results therefore reveal that newly synthesized Dox-Ag (0) NPs had an incredible catalytic and antimicrobial activity as a catalyst. The current findings are equally extendable for safeguarding the aquatic environment against the pollution caused by drugs and microbial activity via a facile, highly economical, rapid and efficient reduction/degradation method supported the catalytic potential of Dox-Ag (0) NPs