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Identification of the risk factors and microbes responsible for inducing central line blood stream infection at a ministry of health hospital in Egypt

Nahla Shaaban Khalil*, Manal Sayed Ismaeel & Gehan Abd Naby Mohamed

Aim of the study: To identify the risk factors and microbes responsible for inducing central line blood stream infection and study the antibiotic sensitivity patterns of the isolated organisms in critically ill patients in ICU setting. Design setting and participants: A descriptive exploratory design was used utilizing non probability convenient sample consisting of 120 adult patients who underwent insertion of central venous catheter in the Intensive Care Units at one of a Ministry of Health Hospital in Egypt between September 2016 and September 2017. Methods: Patients' demographic data, clinical characteristics, blood culture, antibiotic sensitivity test and catheterrelated data were utilized in data collection from patients, records and microbiology laboratory. Results: Out of 120 central line catheters sent for culture from patients during and seven days after insertion revealed no growth during insertion and 10.83% were colonized after insertion. Of the 13 catheter infections cases, it revealed that 10(76.9%) were Staphylococcus epidermis and 3 (23.07%) were Staphylococcus aureus. In addition, most infected patients were overweight and obese, diabetic, had sub-clavian route, and their length of hospital stayed more than 7 day. Conclusions and recommendations: Conclusions and recommendations: Central line venous catheter related factors are the contributing factors for inducing infection of cases with Staphylococcus epidermis in the present study. Moreover, replication of the study and further researches are recommended on a larger probability sample to validate findings.