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Neurovascular Behçet's Disease: Inflammatory Disorder of the Central Nervous System Blood Vessels

Keem Zeang

Neurovascular Disease is a rare and intricate subset of Behçet's syndrome, an autoimmune disorder characterized by systemic inflammation. This condition primarily affects the central nervous system and blood vessels, leading to a diverse range of neurological symptoms and vascular complications. The etiology of Neuro-Behçet's Disease remains incompletely understood, but it is believed to result from aberrant immune responses and genetic predispositions. Overview of the clinical features, diagnostic criteria, and management of Neuro-Behçet's Disease. Patients often present with recurrent episodes of headache, cognitive impairment, and various neurological deficits. Magnetic resonance imaging (MRI) and cerebrospinal fluid analysis are crucial tools for diagnosis, although the absence of specific biomarkers poses diagnostic challenges. The management of Neuro-Behçet's Disease typically involves immunosuppressive therapies, such as corticosteroids and disease-modifying antirheumatic drugs (DMARDs). In more severe cases, biologic agents may be considered. Multidisciplinary care involving neurologists, rheumatologists, and vascular specialists is essential to tailor treatment plans to individual patients and address the multifaceted nature of the disease. The complexity of Neuro-Behçet's Disease and underscores the importance of early diagnosis and comprehensive management strategies to mitigate the often debilitating impact on patients' quality of life.