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Studies on anti-inflammatory effects of an injectable copolymer of fatty acids (Ara 3000 beta)

Bauge C, Beck C, Devaux E, Ewert G and Boumediene K

Osteoarthritis (OA) is the most common musculoskeletal disease. It is a long-term chronic disease involving the thinning of cartilage in joints which results in bones rubbing together, creating stiffness, pain, and impaired movement. The current control strategy mainly consists in palliative pain treatment, and there are several medicines on the market that alleviate pain and improve function in OA patients. The identification of new therapeutic drugs or procedures could improve the patient quality of life. Recently, the benefice of fatty acids has emerged. In particular, our work published in Journal of Inflammation highlights, by in vitro and in vivo experiments, the anti-inflammatory effects of an injectable copolymer of fatty acid (Ara 3000 beta®) in joints.