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Understanding Drug-Receptor Interactions: Unlocking the Secrets of Pharmacology
Dr. Suman ShimlaDrug-receptor interactions constitute a fundamental mechanism underlying the pharmacological effects of therapeutic agents and the elucidation of their mechanisms of action. This intricate interplay involves the binding of drugs to specific receptors, often proteins, within the body. This interaction triggers a cascade of molecular events that ultimately influence cellular responses, physiological processes, and therapeutic outcomes. Understanding the intricacies of drug-receptor interactions is pivotal for drug discovery, design, and optimization. This abstract delves into the complexities of drug-receptor interactions, highlighting their significance in pharmacology, their underlying molecular mechanisms, and the approaches used to study and manipulate these interactions for improved therapeutic interventions. Drug-receptor interactions play a pivotal role in the field of pharmacology by elucidating the mechanisms through which drugs exert their therapeutic effects or adverse reactions. This complex interplay involves the binding of a drug molecule to a specific cellular target, usually a protein receptor, leading to a cascade of biochemical events that modulate cellular functions. Understanding the intricacies of drug-receptor interactions is critical for the rational design of drugs, optimization of therapeutic outcomes, and mitigation of potential side effects. This review delves into the fundamental concepts underlying drug-receptor interactions, highlighting key molecular and structural aspects, as well as exploring the various types of interactions and their implications for drug discovery and development