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Usefulness of diffusion-weighted MRI in the characterization and assessment of response to neoadjuvant therapy in rectal cancer

Luis Curvo-Semedo

The following article will focus on the role of diffusion-weighted MRI for the assessment of response to neoadjuvant combined chemoradiation therapy in rectal cancer patients. The interest of diffusion-weighted imaging for tumor characterization will be discussed, as well as the evaluation of clearance from the mesorectal fascia, nodal downstaging, assessment of complete response and the prediction of response before and during combined chemoradiation therapy.