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Current frontiers in the clinical research of coronary physiology

D Corcoran, C Berry & K Oldroyd

Assessment of coronary physiology has potential diagnostic value when combined with invasive angiography for the assessment and treatment of patients presenting with chest pain. In this article, we review the rationale and evidence base f r the measurement of fractional flow reserve, coronary flow reserve and the index f microvascular resistance in stable coronary artery disease and in acute c r nary syndromes. The current and future role of these physiological tests in utine clinical practice is also considered.