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Fetal Cardiac Calcifications: Report of Four Prenatally Diagnosed Cases and Review of the Literature

Moatasem Bellah Al Farrah

Fetal cardiac calcifications are defined as diffuse hyperechogenicities in the different layers
of the heart. This is an uncommon fetal ultrasound finding associated with significant
myocardial dysfunction. We report four cases with massive fetal myocardial calcifications
detected on prenatal ultrasound at 18-22 weeks’ gestation and associated, in all cases, with
significant cardiac dysfunction. Detailed fetal echocardiographic evaluation, chromosome
analysis, and an extensive search for intrauterine infection as a cause of these abnormalities,
were carried out on all cases.